Hirohiko Hirano Selected Research

Polypharmacy

1/2024	Associations of polypharmacy with frailty severity and each frailty phenotype in community-dwelling older adults: Itabashi Longitudinal Study on Aging.
3/2022	Xerostomia as a key predictor of physical frailty among community-dwelling older adults in Japan: a five-year prospective cohort study from The Otassha Study.
11/2020	Association between anorexia and hyposalivation in community-dwelling older adults in Japan: a 6-year longitudinal study.

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Hirohiko Hirano Research Topics

Disease

12	Frailty 05/2024 - 01/2017
8	Sarcopenia 01/2023 - 01/2015
6	Dementia (Dementias) 01/2023 - 07/2012
5	Weight Loss (Weight Reduction) 01/2024 - 01/2016
5	Malnutrition (Nutritional Deficiencies) 08/2022 - 01/2016
4	Xerostomia 03/2022 - 03/2016
4	Deglutition Disorders (Dysphagia) 01/2022 - 07/2012
3	Tooth Loss 02/2023 - 01/2003
3	Cognitive Dysfunction 07/2021 - 01/2021
3	Heart Diseases (Heart Disease) 05/2018 - 01/2011
2	Airway Obstruction (Choking) 10/2022 - 01/2017
2	Prediabetic State (Prediabetes) 01/2022 - 07/2018
2	Anorexia 01/2022 - 11/2020
2	Neoplasms (Cancer) 01/2017 - 01/2016
1	Periodontal Diseases (Periodontal Disease) 02/2023
1	Alzheimer Disease (Alzheimer's Disease) 01/2023
1	Inflammation (Inflammations) 01/2023
1	Anxiety Disorders (Anxiety Disorder) 10/2022
1	Agoraphobia 10/2022
1	Major Depressive Disorder (Major Depressive Disorders) 10/2022
1	Sepsis (Septicemia) 01/2022
1	Type 2 Diabetes Mellitus (MODY) 01/2022
1	Fever (Fevers) 01/2022
1	Chronic Disease (Chronic Diseases) 01/2021
1	Acinar Cell Carcinoma 01/2021
1	Stroke (Strokes) 01/2021
1	Vitreous Detachment (Posterior Vitreous Detachment) 10/2020
1	Mental Disorders (Mental Disorder) 10/2018
1	Skeletal Abnormalities Mandibular Hypoplasia Auditory Canal Atresia Short Stature 04/2018
1	Stomatitis 01/2018
1	Hematologic Diseases (Blood Diseases) 01/2018
1	Knee Osteoarthritis 11/2017
1	Diabetes Mellitus 01/2017
1	Neoplasm Metastasis (Metastasis) 01/2017
1	Hypertension (High Blood Pressure) 01/2017
1	Hypersensitivity (Allergy) 01/2017
1	Dental Plaque 08/2016
1	Mobility Limitation (Difficulty Walking) 04/2015
1	Osteoarthritis 04/2015
1	Urinary Incontinence 04/2015
1	Low Back Pain (Lumbago) 04/2015
1	Contracture 07/2014

Drug/Important Bio-Agent (IBA)

6	Serum AlbuminIBA 01/2021 - 07/2014
4	Proteins (Proteins, Gene)FDA Link 08/2022 - 01/2017
3	AlbuminsIBA 05/2018 - 01/2016
2	Indicators and Reagents (Reagents)IBA 05/2024 - 04/2018
2	Vitamin D FDA LinkGeneric 01/2023 - 01/2021
2	Biomarkers (Surrogate Marker)IBA 10/2022 - 10/2018
2	Retinaldehyde (Retinal)IBA 01/2022 - 10/2020
2	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2021 - 10/2018
2	A-factor (Streptomyces)IBA 09/2018 - 07/2012
2	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 04/2018 - 01/2017
1	Chewing Gum (Chewing Gums)IBA 12/2023
1	cyclopropapyrroloindoleIBA 02/2023
1	ElementsIBA 02/2023
1	TeaIBA 10/2022
1	Blood Glucose (Blood Sugar)IBA 01/2022
1	Insulin (Novolin)FDA Link 01/2022
1	KetonesIBA 01/2022
1	bis(N,N- dimethylhydroxamido)hydroxooxovanadateIBA 02/2021
1	IronIBA 01/2021
1	MagnesiumIBA 01/2021
1	Folic Acid (Vitamin M)FDA LinkGeneric 01/2021
1	Vitamin E FDA LinkGeneric 01/2021
1	Vitamin K FDA Link 01/2021
1	CalciumIBA 01/2021
1	Ascorbic Acid (Vitamin C)FDA LinkGeneric 01/2021
1	2-methylcyclopentadienyl manganese tricarbonyl (MMT)IBA 09/2018
1	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 07/2018
1	Triglycerides (Triacylglycerol)IBA 01/2017
1	tetranectinIBA 01/2017
1	Hypnotics and Sedatives (Sedatives)IBA 03/2016
1	Cystatin CIBA 01/2015
1	Analgesics (Analgesic Drugs)IBA 01/2011
1	Matrix Gla ProteinIBA 01/2003

Therapy/Procedure

11	Long-Term Care 05/2024 - 10/2015
4	Oral Hygiene (Dental Hygiene) 01/2023 - 08/2016
4	Bite Force (Occlusal Forces) 01/2023 - 01/2017
4	Activities of Daily Living (ADL) 01/2022 - 04/2015
3	Polypharmacy 01/2024 - 11/2020
2	Nursing Care 01/2022 - 10/2021
2	Dentures 01/2022 - 07/2021
2	Therapeutics 01/2022 - 01/2018
1	Dental Care 06/2021
1	Local Anesthesia 01/2021
1	Oral Diagnosis (Oral Examination) 01/2018
1	Tooth Extraction (Tooth Extractions) 01/2018
1	Transplantation 01/2018
1	Palliative Care (Palliative Therapy) 01/2016